Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Generic brand of plaquenil Test done before plaquenil Chloroquine and primaquine dose Plaquenil’s long half-life in the body can cause irreversible and progressive damage, Dr. Fung said. Similarly, one study reported that 16 women who’d taken hydroxychloroquine or chloroquine, or a combination of the agents, showed no improvement seven years after stopping drug therapy, and progression occurred in six of the cases. 2 Seatx & Living5oul. I have never read that Plaquenil carries a high risk of being a contributing factor to anemia. My hardcover does mention a very uncommon problem with Plaquenil causing hair to change to gray, damage to muscle cells, and "lower blood counts"---but these side effects occur so says my hardcover. Iron deficiency anaemia is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 6 - 12 months, also take medication Enbrel, and have Preventive health care. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Can plaquenil cause anemia Will you have Aplastic anemia with Plaquenil - eHealthMe, Healthboards - Immune & Autoimmune - Lupus Anemia anyone How to pay for plaquenilPlaquenil and effexorSulfasalazine vs hydroxychloroquineChloroquine phosphate tablets ip 500mgMaculopathy plaquenil While pernicious anemia is defined as anemia resulting from inadequate absorption of vitamin B-12 from the gastrointestinal tract due to the autoimmune process described above, other causes of vitamin B-12 deficiency can also produce the characteristic signs and symptoms of pernicious anemia. Other potential causes of vitamin B-12 deficiency. Pernicious Anemia Vitamin B-12 Deficiency Symptoms and Signs Causes. Will you have Iron deficiency anaemia with Plaquenil - eHealthMe. Symptoms of Sjögren's Syndrome - Johns Hopkins Sjogrens Center. According to the New Zealand Dermatological Society, Plaquenil can cause abnormalities in blood counts. An abnormally low number of white blood cells can lead to infection, because white blood cells defend the body against bacteria. Low platelet count thrombocytopenia can lead to easy bleeding and bruising. Jan 24, 2011 I have anemia and had it prior to taking Plaquenil. My hematologist did tell me last week that Plaquenil can lower one's readings. Raynauds, sero-negative RA, Primary SjS, osteopenia, degenerative disc disease, disc protrusions,stenosis, Carpal tunnel, poly neuropathy, myoclonus, hiatal hernia, esophagitis. Many diseases can cause extreme fatigue and weakness. Anemia can cause extreme fatigue and weakness. The Mayo Clinic website reports that anemia occurs when a person lacks sufficient red blood cells or iron to carry oxygen to her tissues and organs and that a person with anemia will experience weakness and fatigue.