Please review the following URL and make sure that it is spelled correctly. Hydroxychloroquine (Plaquenil) is considered a disease-modifying anti-rheumatic drug (DMARD). Chloroquine and proguanil brand Malaria prophylaxis with chloroquine Hi, I have lyme disease and have frequently been on plaquenil only in the summer as stronger drugs are used when I'm not in the sun and I've yet to experience this. But I do know that it is often used to prevent and treat malaria and that many drugs that deal with such things have a tendency to cause some crazy dreams. Your muscles are controlled by electrical impulses sent from nerves. Lyme is a neurotoxic bacteria. When the Lyme invades your nervous system, it can do whatever it wants to, whenever it wants to. It's only another reason why the disease is so debilitating because you can't control it or even predict when a flare up could occur. She had been diagnosed with Lyme disease seven years earlier. Sue felt sure that her Lyme had been “successfully treated with alternative remedies.” But still, she suffers from tight jaw muscles, intense pain when she lays her face on a pillow, fragile emotions that prompt daily outbursts of crying, and “raging pain in my face and jaw”. It may prevent joint damage and reduce the risk of long-term disability. It can decrease the pain and swelling of arthritis. Plaquenil lyme disease and muscle pain Lyme Carditis When Lyme Disease Involves Your Heart, Muscle Weakness and Lyme Disease - Tired of Lyme Plaquenil capsule appearance Mar 16, 2009 I am taking amoxi for the lyme spirrochete. about two weeks after starting it, I assume the pain in my arm and back is a herx. I quit levaquin 3 days ago until this pain goes away, just in case. I am going to wait until the pain subsides before starting either levaquin again or plaqenil. Plaquenil questions -. Can Lyme Disease Cause TMJ? - Donald R. Tanenbaum, DDS MPH. Lyme Disease Neuropathy The Foundation For Peripheral Neuropathy. The signs and symptoms of Lyme disease vary. They usually appear in stages, but the stages can overlap. Early signs and symptoms. A small, red bump, similar to the bump of a mosquito bite, often appears at the site of a tick bite or tick removal and resolves over a few days. Initially, Lyme disease will produce flu-like symptoms, fatigue, and a bull’s-eye pattern rash. Joint pain and muscle weakness may develop following treatment of the infection. In this blog, the pain management specialists at Tulsa Pain explain what can be done to manage the long-term effects of Lyme disease. Lyme disease is a multi-system bacterial infection which is transmitted to humans through the bite of an infected deer tick. In this Lyme Disease Video Series, Dr. Aucott walks through Lyme Disease including disease overview, signs and symptoms, diagnosis, treatment and prognosis.