While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners. "Hydrochloroquine (Plaquenil) has been a blessing for me. Chloroquine high Chloroquine tablet price Tylenol and plaquenil No methotrexate doesn't always mean your hair will fall out or thin but some of the side effects are scary, but before you an progress onto other meds methotrexate is mandatory. for me methotreaxte and plaquenil does't work and i' intonate of sulfa so i am started embrel which states you have to have tried 2 of 3 meds and methotrexate is 1 of them. Hydroxychloroquine is a DMARD. The brand name is Plaquenil. What does Plaquenil do? Plaquenil relieves pain and swelling and prevents damage to joints. How long does Plaquenil take to work? Plaquenil works very slowly. In 1 to 3 months you should start to feel better. You may continue to get better for up to 1 year. Dec 10, 2012 Med to try when plaquenil doesn't work? on December 10, 2012, AM My understanding, from reading here, is that plaquenil is a good "first line" med for treating autoimmune disorders. I do occasionally experience dry eyes and a little scalp itch but asserting that it's caused by Hydrochloroquine would be anecdotal at best. It took about 5 weeks to take effect but my RA is basically a non factor now. When plaquenil doesn t work What step comes after plaquenil?, Lupus Medicines Hydroxychloroquine - Brigham and Women's. Chloroquine cost canadaChloroquine sold whereHydroxychloroquine and sun exposureZydus hydroxychloroquine side effectsPlaquenil and vision problems Re Plaquenil not working anymore Lizzy, I took 400mg 200 twice a day for 16-18 months forget exact duration, then was reduced to 200 mg daily. But right from the start, I also needed NSAID's for pain. Immune & Autoimmune - Lupus Plaquenil not working anymore. Med to try when plaquenil doesn't work? - Sjogren's World. Treating Lupus with Anti-Malarial Drugs Johns Hopkins.. Health related message boards offering discussions of numerous health topics including allergies, cancer, diabetes, heart disease, exercise, attention deficit disorder, diet, and nutrition. Arthritis Board Index plaquenil how long to work Hydroxychloroquine doesn’t work immediately. It may be 12 weeks or longer before you notice any benefit. Because it's a long-term treatment it's important to keep taking hydroxychloroquine unless you have severe side-effects even if it doesn't seem to be working at first; even when your symptoms improve to help keep the disease under control. Does anyone take methotrexate and hydroxychloroquine and has anyone had problems with hydroxychloroquine. No joke I had to come off purely because I thought I was going to take off in work. Not good for credibility let me tell you xxxx Fi. Reply 0 Report. Hidden. in reply to Hidden.