One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine (Plaquenil), a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Chloroquine phosphate tablets used for Can plaquenil can tooth decay When the clinician that detects early retinopathy does not discontinue CQ/HCQ therapy, the prognosis is a progressive loss of paracentral vision followed by loss of central vision and night blindness. Even when the clinician discontinues therapy, retinopathy can progress for many years. A recent update of the American Association of Ophtalmology AAO recommendations on screening for chloroquine and hydroxychloroquine retinopathy, suggests to screen patients under AM treatment. Hydroxychloroquine HCQ is efficacious for various diseases1,2, but can produce “bulls-eye” retinopathy that decreases vision even after discontinuance3,4. Retinopathy can be present in 7.5% of patients after 5 or more years of HCQ treatment, increasing to 20% after 20 years2. It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress. Downes sm hydroxychloroquine retinopathy Hydroxychloroquine-Induced Retinal Toxicity - American., FRI0639 A NOVEL SCREENING METHOD FOR HYDROXYCHLOROQUINE. Plaquenil and celexa interactionChloroquine cancerPlaquenil granuloma annulareHydroxychloroquine side effects anxietyPlaquenil max dosage mg kg An uncommon, but serious, side effect that has been attributed to hydroxychloroquine is retinopathy that can cause visual field deficits, visual disturbances, macular degeneration, decreased dark adaptation, and color vision abnormalities. 1,2 This effect is dose related and if not identified in its early stages, may be irreversible. What are the side effects of hydroxychloroquine Plaquenil.. Hydroxychloroquine Ocular Toxicity Lessons Learned The.. Hydroxychloroquine retinopathy. - Abstract - Europe PMC. Of our 31 patients with a diagnosis of blindness or toxic maculopathy, 11 had documented blindness, in all cases attributed to a cause other than HCQ-related ocular toxicity stroke 27%, pre-existing macular disease 18%, diabetic retinopathy 18%, hypertensive retinopathy 9% and cataracts 9%. Hydroxychloroquine toxicity Hydroxychloroquine HCQ is a drug used in the treatment of rheumatological and dermatological disorders. Its big brother, chloroquine, used to be highly toxic, however, despite its improved safety profile retinal toxicity is a significant and potentially sight-threatening risk. Abstract Background The American Academy of Ophthalmology recommendations on screening for chloroquine CQ and hydroxychloroquine HCQ retinopathy are revised in light of new information about the prevalence of toxicity, risk factors, fundus distribution, and effectiveness of screening tools.