Affecting my self esteem Your definitely not alone. I’m fair hair n skin but I’m getting brown blotches. I am not looking to when it starts coming down my face hope I can b helped in time. Rheumatoid arthritis methotrexate therapy hydroxychloroquine monotherapy Chloroquine autophagy cancer Hydroxychloroquine action Sep 13, 2019 Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Although not all of these side effects may occur, if they do occur. Feb 19, 2020 SIDE EFFECTS. The following adverse reactions have been identified during post-approval use of PLAQUENIL or other 4-aminoqunoline compounds. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. Some of these long-term users will develop grayish-blue pigmentation on. Pigmentation associated with long-term use of Plaquenil. their shins and forearms. The discoloration is now considered to be more likely to occur in thin skin that gets easily traumatized, especially if superficial bleeding occurred in the bruises. My scalp has turned black and my forehead side of face r slowly turning ears r totally black shiny plate .various long and boring treatments from docs but to no avail.finally I have been asked to stopped taking h for lupus for 3 next step will b decided. I am surprised to hear about this cos my rheumy said hydroxy helps to lighten the skin. One of them is on my nose and people keep telling me I’ve a dirt mark. I'm from Indian sub continent and am a "woman of colour like urself" approx 2 years ago had sudden deep painful itch in scalp and body. Yes I have been on this med since 2003 and I have black patches all over. Plaquenil blue skin Common and Rare Side Effects for Plaquenil Oral, Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses Hydroxychloroquine hand osteoarthritis Some medications, such as plaquenil and minocycline, can cause permanent dark skin plaques, which resemble black and blue marks similar to morphea scleroderma. Cosmetically, pigmentation differences can be covered up with corrective cosmetics, such as Dermablend. Drug-Induced Hyperpigmentation caused by Minocycline Minocin Antibiotic Systemic Scleroderma Skin Involvement Hyperpigmentation and.. Plaquenil Use in Autoimmune Diseases. Hydroxychloroquine and skin darkening Hi All. - LUPUS UK. Aug 14, 2013 Hydroxychloroquine-associated hyperpigmentation in an elderly woman was clinically misinterpreted as elder abuse resulting in notification of Adult Protective Services by the clinician; skin biopsy subsequently confirmed the etiology of her diffuse black and blue dyschromia. Yes. Hair bleaching, hair loss, skin pigmentation, rash and itching are recognized skin adverse reactions of plaquenil hydroxychloroquine. These reactions tend to be worse if a patient is taking other medications that have similar skin toxicity. Please consult a dermatologist to ensure skin lesions are not psoriatic because Plaquenil hydroxychloroquine use needs special precautions in. Blue–grey pigmentation of the skin affects up to 25% of patients taking hydroxychloroquine, especially where there has been bruising. Transverse pigmented nail bands and mucosal pigmentation have also been reported. Rashes may occur in up to 10% of patients, most commonly morbilliform or psoriasiform.