Our team periodically reviews articles in order to ensure content quality. The sources cited below consist of evidence from peer-reviewed journals, prominent medical organizations, academic associations, and government data. Folic acid and plaquenil Plaquenil and hair color Anxiety and Plaquenil. On a whim, I did a search for plaquenil and anxiety. I was shocked to see that anxiety is a side effect. Maybe I'm not crazy after all. Does anyone have similar story to share. 5mg a day for 5 to 6 years and your symptoms you described, can be some of the side effects from prednisone? Do you by chance take. I've been on Plaquenil 200 mg twice a day for almost three weeks now. Also Doxycycline 100 mg three times a day up until this Monday, when I switched to Biaxin 500 mg twice a day. Since about three days into treatment, I have had anxiety that is just getting worse and worse. I honestly don't know if it's a herx or a side effect. Plaquenil Side Effects by Likelihood and Severity INFREQUENT side effects. If experienced, these tend to have a Severe expression. A Disorder Of The Retina Of The Eye;. RARE side effects. Please check with the appropriate physician regarding health questions and concerns. The information contained on this site is for informational purposes only, and should not be used as a substitute for the advice of a professional health care provider. Plaquenil anxiety side effect Plaquenil Oral Uses, Side Effects, Interactions., Can Plaquenil cause anxiety as a side effect, not a herx? Where can i buy chloroquineDoes plaquenil make a virus worseChloroquine sensitive Tell your doctor if any of the following side effects, as they may be indications of a more serious reaction Headache. Loss of appetite. Dizziness. Nausea. Diarrhea, vomiting, or stomach pain. Skin rash. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. Common and Rare Side Effects for Plaquenil Oral. Will you have Stress and anxiety with Plaquenil - eHealthMe. Plaquenil Side Effects of Anxiety and Depression? I've been on plaquenil for a very long time - maybe 15 years. I saw a new rhuemie today who said I should take a break & see how I feel with some anti-inflammatories, a good diet, exercise and rest. Note This document contains side effect information about hydroxychloroquine. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Plaquenil side effects Get emergency medical help if you have signs of an allergic reaction to Plaquenil hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Taking Plaquenil long-term or at high doses may cause irreversible damage to the retina of your eye.