Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Chloroquine drug action Plaquenil and joint repla Plaquenil 10 mg Plaquenil tabletas Hair bleaching, hair loss, skin pigmentation, rash and itching are recognized skin adverse reactions of plaquenil hydroxychloroquine. These reactions tend to be worse if a patient is taking other medications that have similar skin toxicity. Please consult a dermatologist to ensure skin lesions are not psoriatic because Plaquenil hydroxychloroquine use needs special precautions in psoriasis. RA medications may be the cause of rashes on a person’s skin. These rashes are believed to be allergic reactions to the medications. Medications that may cause a rash include tolmetin; celecoxib Itching From Plaquenil. I started taking Plaquenil on June 24th and for the last four or 5 days have had horrible itching. No rash just all over itching. My Rhuemy told me to stop taking it until all itching symptoms were gone, then wait another week and start up again with 1 pill 200mg a day instead of 2 pills. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Does plaquenil cause itchy skin Does plaquenil cause itching - Answers, Rheumatoid arthritis rash Causes, symptoms, and images Treatment of rheumatoid arthritis with methotrexate and hydroxychloroquineChloroquine online pharmacy For the first month I was on Plaquenil my hand and lower arms and lower legs were itchy and had some of the little blisters, my skin got discolored and I had little weird pains in my skin of my lower legs. After about a month it all stopped except the light brown discoloration stayed. Plaquenil and skin DailyStrength. Itching From Plaquenil DailyStrength. Plaquenil Oral Uses, Side Effects, Interactions, Pictures.. Sep 13, 2007 Yes with plaquenil generic, I have itching, intense I could scratch through my skin. But it does calm down. I also get weird rashes but I get those from the Lupus. I find the disease is being treated and the med is attacking the inflammation, so one of the first places inflammation shows up is the skin since it is the largest organ we have. Plaquenil has beneficial effects on 3 major aspects of lupus; skin rashes, aches & pains and fatigue. It has also been found to help in a number of other features of the disease, though less predictably. It is very effective in the treatment of a whole variety of lupus skin rashes, particularly those found to be worsened by sunlight. Usually, a skin biopsy is used to diagnose forms of cutaneous lupus, and various medications are available for treatment, including steroid ointments, corticosteroids e.g. prednisone, and antimalarials e.g. Plaquenil. Chronic Cutaneous Lupus Erythematosus CCLE / Discoid Lupus Erythematosus DLE.