In the UK an estimated 8.5 million people are affected by OA, causing an enormous burden to health authorities, as well as considerable pain and disability to these individuals. A recent study by Arthritis Care reported that 81% of people with OA experience constant pain and 72% have important related conditions, such as high blood pressure or depression. Ocular side effects of chloroquine therapy Plaquenil labs Plaquenil y alcohol Plaquenil medication insert The Hydroxychloroquine Effectiveness in Reducing symptoms of hand Osteoarthritis HERO trial determined the effectiveness of HCQ in treating hand osteoarthritis as an analgesic treatment compared. HERO Trial - Hydroxychloroquine Fails in Hand Osteoarthritis. UK researchers have treated 248 patients with moderate to severe hand pain and radiographic osteoarthritis OA and demonstrated no benefit after 12 months of hydroxychloroquine HCQ, according to a recent article in Annals of Internal Medicine. We believe that hydroxychloroquine may be an effective treatment for reducing inflammation in hand OA and that this reduction in inflammation will lead to a reduction in pain. The primary aim of this study is to determine whether hydroxychloroquine is effective at relieving pain in people with painful hand OA. However, despite the prevalence of hand OA, there are still limited treatment options. Hand OA is generally considered to be less important and less disabling than knee or hip OA, but 8% of the UK population are estimated to be effected by painful hand OA, with a large proportion reporting significant difficulties with common day-to-day tasks, leading to reduced capacity to work and impacting on both quality of life and general health. Hero study hydroxychloroquine Hydroxychloroquine and Risk of Diabetes in Patients With., HERO Trial - Hydroxychloroquine Fails in Hand Osteoarthritis. Chloroquine 500 mgMouth sores plaquenil help Introduction Hydroxychloroquine is widely used in treatment of cutaneous sarcoidosis. There is limited literature regarding the experience of hydroxychloroquine in pulmonary sarcoidosis. Aim To review the treatment and toxicity profile of hydroxychloroquine in the treatment of pulmonary sarcoidosis. Methods Retrospective observational cohort study of sarcoidosis patients in the West of. Experience of hydroxychloroquine in the treatment of.. Does hydroxychloroquine provide effective pain relief for.. Hydroxychloroquine Uses, Dosage & Side Effects -. With hydroxychloroquine will be a practical and safe treatment to reduce synovitis and pain. Methods/design HERO is an investigator-initiated, multicentre, randomized, double-blind, placebo-controlled trial. A total of 252 subjects with symptomatic hand OA will be recruited across primary and secondary care sites in the Discussion The HERO trial is designed to examine whether hydroxychloroquine is an effective analgesic treatment for OA and whether it provides any long-term structural benefit. The ultrasound substudy will address whether baseline synovitis is a predictor of therapeutic response. The study was hosted at the York Trials Unit YTU, University of York. The HERO Trial Hydroxychloroquine Effectiveness in Reducing Symptoms of Hand Osteoarthritis Trial shows there was no benefit in taking hydroxychloroquine to control debilitating pain when compared to a placebo.