If a patient is overweight, one should use the ideal body weight to assess whether the doaily dose is in the toxic range (/= 6.5 mg/kg/day). This graph shows various formulas that have been proposed for deriving ideal body weight for women, because virtually all cases of hydroxychloroquine toxicity have been female. Hydroxychloroquine sulfate uses Sjogren's plaquenil reddit The most recent 2016 guidelines from the American Academy of Ophthalmology AAO recommend the dose of HCQ ≤5 mg/kg real body weight to minimize toxicity 1. According to these new guidelines, the risk of HCQ retinal toxicity is less than 1 % in the first year of therapy and less than 2 % up to 10 years of therapy. A total dose representing 25 mg of base per kg of body weight is administered in three days, as follows First dose 10 mg base per kg but not exceeding a single dose of 620 mg base. Second dose 5 mg base per kg but not exceeding a single dose of 310 mg base 6 hours after first dose. The usual hydroxychloroquine dose that is prescribed is 400 mg/day. For this dosage, any woman with an ideal body weight less than 135 pounds would be in the toxic dose range. As one can see, the height that corresponds to an ideal body weight of 135 pounds varies across the formulas. For this dosage, any woman with an ideal body weight less than 135 pounds would be in the toxic dose range. The usual hydroxychloroquine dose that is prescribed is 400 mg/day. Plaquenil dosing ideal body weight ACR Actual-weight hydroxychloroquine dosing works in SLE, up to a., DailyMed - PLAQUENIL- hydroxychloroquine sulfate tablet Buy aralenHow does chloroquine work against malariaTreatment rheumatoid arthritis with methotrexate and hydroxychloroquineChloroquine still effective for malaria prophylaxis guatamala Furthermore, the co-authors found that the prevalence of toxicity relative to real body weight dosing was independent of body habitus, while thin individuals dosed by ideal body weight had a much. Despite Plaquenil dosing recommendations, retinal toxicity remains. Ideal Body Weight for Calculating Hydroxychloroquine Dosage. Hydroxychloroquine Plaquenil Dosing Calculator - MDCalc. The American Academy of Ophthalmology AAO currently defines an overdose of hydroxychloroquine as more than 5.0 milligrams mg per kilogram kg of body weight 1 kg equals 2.2 pounds or more than 400 mg a day. The maximum dose of Plaquenil is 6.5 mg/kg of ideal body weight per day, regardless of whether a person is overweight, underweight, or normal weight. One kilogram kg equals 2.2 pounds. Women with lupus who are OVER their ideal body weight should go by these dosing rules 5’ 7” or higher - up to 400 mg Plaquenil daily; 5’ 1/2” to 5. Initial dose 400 mg 310 mg base orally 1 to 2 times a day; this dose may be continued for several weeks or months, depending on patient response. Maintenance dose 200 to 400 mg 155 to 310 mg base orally daily. Comments -Each dose should be taken with a meal or a glass of milk.