I've been taking it for about 6 months now, and I can't tell that it's done a thing. I think I may be overmedicated and was thinking about dropping the plaquenil if there was no benefit to it. Thanks, Elcamino Hi Elcamino, I have been taking Plaquenil (400 mg per day) for about 2 years now due to lupus flare. Chloroquine kras Joint task force-bravo chloroquine 1989 Sle plaquenil Rheumatoid arthritis; discoid and systemic lupus erythematosus SLE. Over the long term hydroxychloroquine can reduce pain, swelling and joint stiffness. If you have lupus, it may also improve the rash. It may be as long as 12 weeks before you notice the benefits. Hydroxychloroquine is often taken in combination with other drugs such as. Hello, I thought fatigue is one of the symptoms of RA, so taking the right medication should help lessen fatigue, shouldn't it? When I was diagnosed with RA 2.5 years ago, I experienced fatigue and really bad pain on my foot, but since I started Plaquenil and Orencia 2 years ago, I have been in medically induced remission and don't have fatigue anymore. Nov 14, 2006 Someone else told me that plaquenil could take up to a year to work. Others have told me that it only took a few months for them to feel the effects. Everyone is different. I can tell you that plaquenil is the safest of all of the DMARDs. If you're going to stay on a DMARD for a long time, plaquenil is the one to be on. Best of luck on the. Actually I started on 200 mg per day and about 2 months before tapering off pred, he upped me to 400 mg per day of plaquenil to give it plenty of time to kick in. When i first started it, I was also started on prednisone to get my inflammation under control. How long does plaquenil take to work for ra Hydroxychloroquine Side Effects, Dosage, Uses, and More, Plaquenil for fatigue and pain DailyStrength Natural alternatives plaquenilChloroquine cellsDoes plaquenil reduce spleen inflammationPlaquenil use icd 10 Plaquenil is also used for long-term treatment of autoimmune diseases such as rheumatoid arthritis RA and systemic lupus erythmatosis. According to the Mayo Clinic, it can take up to six months' constant use before an effect is seen in RA 1. Plaquenil can cause serious side effects when used in high doses for chronic diseases such as RA over. Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis. Plaquenil -. Plaquenil - HealthBoards. Here are 10 things to keep in mind when using Plaquenil Take it on a regular schedule, meaning at the same time each day. Take Plaquenil EXACTLY as prescribed by your physician. Do not stop taking the medication without first speaking to your doctor. Taking Hydroxychloroquine with food and/or milk can help prevent stomach upset. Rated Hydroxychloroquine for Rheumatoid Arthritis Report Plaquenil was a miracle drug for me. It began to work in 3 weeks and within 6 months my inflammation had gone from over 40 to 5.5. Kids shouldn't take Plaquenil as a long-term treatment. To treat rheumatoid arthritis, the dosage is higher, with one to three tablets typically taken once a day. If you miss a dose of.