Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Hydroxychloroquine during infection Trade name chloroquine Take it once weekly while in the area, and continue taking it for 4 to 8 weeks after leaving the area or as directed by your doctor. To treat malaria, follow your doctor's lupus or rheumatoid arthritis, take this medication by mouth, usually once or twice daily or as directed. Your doctor may gradually increase your dose. However, these are all so minor when I compare to the good plaquenil is doing in my life. I don't want to have my joints deterioriate and not be able to do the things I love. I don't want my diseases to affect my internal organs and take my life away. Plaquenil can save and extend your life. Please consider taking your doctor's advice. Overall Plaquenil did take away the muscle and joint pain. It worked wonders for that. For that reason I am satisfied with plaquenil for what I took it for. Took about 5-6 months to see full effect. Since reducing the dose from 400mg to 200mg 4 months ago I do feel some of this pain returning You win some, you lose some! M 49 Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Will plaquenil take joint swelling away What next if plaquenil doesn't work? -, Plaquenil Hydroxycholorquine - Arthritis - MedHelp What does plaquenil treatHydroxychloroquine medline plusPrimary care prescribe plaquenilTier for hydroxychloroquineChloroquine tablet Plaquenil stays in your body for about 3 months. If you must stop it, it will take a while for the side effects to go away. You should have an eye examination every year to prevent a very rare but serious eye problem. Less than one person in 5,000 develops the problem. Lupus Medicines Hydroxychloroquine - Brigham and Women's.. PLAQUENIL Side Effects, Reviews by Patients -. PLAQUENIL" Rheumatoid Arthritis Community - Support Group. Stars. Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. I noticed plaquenil helping with my fatigue more so than anything else. It does help my joint pain but I need extra help from other meds too It can take up to 6 months to get in your system and fully work, each person is different. I pray it doesn't take that long for you to get some relief. Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more.