Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Flu shot and plaquenil Hydroxychloroquine increase creatinine Hydroxychloroquine Causes Severe Vacuolar Myopathy in a Patient With Chronic Graft-Versus-Host Disease Javier Bolan˜os-Meade,1 Lan Zhou,2 Ahmet Hoke,2 Andrea Corse,2 Georgia Vogelsang,1 and Kathryn R. Wagner2* 1Department of Oncology, The Johns Hopkins Hospital, Baltimore, Maryland 2 Department of Neurology, The Johns Hopkins Hospital, Baltimore, Maryland A 51-year-old man developed. Summary We study how severe was Myopathy, when it was recovered, drug effectiveness, race, and more among people who take Plaquenil. This study is created by eHealthMe based on reports of 1,993 people who have side effects when taking Plaquenil from sources other than FDA, and is updated regularly. DIAGNOSIS. Hydroxychloroquine myopathy. DISCUSSION. Hydroxychloroquine HCQ, a commonly used drug for various autoimmune conditions, is widely distributed into cardiac and skeletal muscle tissue. It is a large amphiphilic molecule that can cause both myofiber necrosis and vacuolar myopathy. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Hydroxychloroquine myopathy Common and Rare Side Effects for Hydroxychloroquine Oral, Myopathy in Plaquenil how severe and when it was. Chloroquine injection dosage Hydroxychloroquine is used in the treatment of various rheumatic conditions including systemic lupus erythematous. Hydroxychloroquine induced myopathy is rare adverse reaction but symptoms are usually recover after discontinuation of the drug. Here we report a case of woman with systemic lupus erythematosus who presented with myopathy after eight months treatment with hydroxychloroquine. A Rare but Reversible Cause of Myopathy.. Final Diagnosis -- Hydroxychloroquine myopathy - UPMC. Acquired non-inflammatory myopathy - Wikipedia. Muscle and peripheral nerve toxicity is rare with hydroxychloroquine. Severe vacuolar myopathy has been reported 3 A. A 51-year-old man with a mantle cell carcinoma was initially treated with cyclophosphamide, doxorubicin, vincristine, and prednisolone and obtained remission for 2 years. Moved Permanently. The document has moved here. Hydroxychloroquine induced myopathy is thought to be underestimated because of slightly elevated to normal CK levels 10. Physicians should be aware of this cause of myopathy because hydroxychloroquine is widely used around the world and symptoms usually recover only after cessation of the drug.