It does not work against certain types of malaria (chloroquine-resistant). The United States Center for Disease Control provides updated guidelines and travel recommendations for the prevention and treatment of malaria in different parts of the world. Chloroquine peremption Plaquenil guidelines 2019 Does Diltiazem Hcl Interact with other Medications? Severe Interactions. These medications are not usually taken together. Consult your healthcare professional e.g. doctor or pharmacist for. As PLAQUENIL may enhance the effects of a hypoglycemic treatment, a decrease in doses of insulin or antidiabetic drugs may be required. Drugs That Prolong QT Interval And Other Arrhythmogenic Drugs. PLAQUENIL prolongs the QT interval and should not be administered with other drugs that have the potential to induce cardiac arrhythmias. Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. This medication is also used, usually with other medications, to treat certain auto-immune diseases (lupus, rheumatoid arthritis) when other medications have not worked or cannot be used. Discuss the most recent information with your doctor before traveling to areas where malaria occurs. Diphenhydramine interaction with plaquenil Nortriptyline Oral Interactions with Other Medication, Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects. Chloroquine used whereBenefits of using plaquenilPlaquenil for chronic urticaria Diphenhydramine; Hydrocodone; Phenylephrine Moderate Concomitant use of hydrocodone with hydroxychloroquine may increase hydrocodone plasma concentrations and prolong opioid adverse reactions, including hypotension, respiratory depression, profound sedation, coma, and death. It is recommended to avoid this combination when hydrocodone is being used for cough. Plaquenil hydroxychloroquine sulfate dose, indications, adverse.. Plaquenil Oral Uses, Side Effects, Interactions.. Diphenhydramine Drugs Details. Hydroxychloroquine is used to prevent or treat malaria infections caused by mosquito bites. It does not work against certain types of malaria chloroquine-resistant. The United States Center for. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is. Plaquenil, widely used to treat lupus, rheumatoid arthritis and other inflammatory and dermatologic conditions, is very effective, and “the risk of toxicity in the first five years for someone without special risk factors is very low,” Dr. Marmor said. However, risk increases with duration of use.