Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it. Does hydroxychloroquine suppress the immune system Malaria prophylaxis pregnancy chloroquine Malaria chemoprophylaxis chloroquine phosphate tablet 500 mg Chloroquine diphosphate Catalog No. T0194 CAS 50-63-5 Synonyms Aralen phosphate, Chingamin phosphate Chloroquine is an aminoquinoline antimalarial and also is widely used as an autophagy inhibitor. Directions for Use Chloroquine is supplied as a lyophilized powder. For a 50 mM stock, reconstitute the 150 mg in 5.82 ml sterile dH 2 O. First add 1 ml dH 2 O to the tube containing the chemical, vortex, and dispense into a new, larger tube. Repeat this action two or three more times to transfer any residual mate-rial. Add additional dH 2 Chloroquine is a member of quinolone family and is a weak intercalating agent. Chloroquine is used for treating amebiasis, rheumatoid arthritis, discoid and systemic lupus erythematosus. Application DNA intercalator. Also used to increase transfection efficiency. Chloroquine diphosphate salt has been used • in in vitro antiplasmodial assays The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead. Chloroquine diphosphate stock Chloroquine diphosphate Autophagy Inhibitor MedChemExpress, Chloroquine - Cell Signaling Technology Half life hydroxychloroquine Chloroquine diphosphate Catalog No. T0194 CAS 50-63-5 Synonyms Aralen phosphate, Chingamin phosphate. Chloroquine is an aminoquinoline antimalarial and also is widely used as an autophagy inhibitor. Chloroquine also is an inhibitor of toll-like receptors TLRs. Chloroquine diphosphateATM/ATR activatorbuy chloroquine diphosphate.. Chloroquine diphosphate salt powder or crystals, 98.5-101.. Chloroquine diphosphate Chloroquine Phosphate CAS 50.. Chloroquine diphosphate is used as an antimalarial drug and also functions to increase sensitivity of tumor cells to radiation and chemotherapy via inducing autophagy 1. Chloroquine diphosphate has been reported as an adjuvant for radiation a Chloroquine binds to heme or FP to form the FP-chloroquine complex; this complex is highly toxic to the cell and disrupts membrane function. Action of the toxic FP-chloroquine and FP results in cell lysis and ultimately parasite cell autodigestion. Chloroquine diphosphate. 100 mM Dissolve 60 mg of chloroquine diphosphate in 1 ml of deionized distilled H 2 O. Sterilize the solution by passing it through a 0.22-μm filter. Store the filtrate in foil-wrapped tubes at -20°C.