Over the last six months I began to experience extremely itchy skin - I just wanted to scratch my skin off - sometimes without realising I made my arms bleed. I then, about 5 weeks ago, began to experience my eyes becoming very itchy, on the inside, they became very red and watered continuiously. Plaquenil loss of appetite Chloroquine functional group Does plaquenil have lifetime effects Plaquenil and prednisone for rheumatoid arthritis Severe depression and anxiety, overall itching, pain and stiffness increased instead of decreased First, my mother and sister took plaquenil for lupus with good effect, so I am not just disliking it for no good reason. I also suffer from disabling bipolar disorder. For 25 years, I have gotten hypomanic during spring. Very happy, never depressed. I was dropped from 400mg to 200mg Hydroxy about 6 weeks ago at the same time as I switched to injectable MTX instead of the tablets. I asked why the drop in dose and my GP read the rheumy's email and apparently Hydroxy works cumulatively so that it may be fine but can build up in your system after a period of time and that's why I was put on the lower dose as a maintenance dose so that the. Plaquenil is prescribed as a disease-modifier, in other words, to decrease pain, decrease swelling, and prevent joint damage and disability. It is not known how Plaquenil works but researchers believe that Plaquenil interferes with communication between cells within the immune system. Ultimately, it is thought to block proinflammatory. I could not go to work looking as I did, so I stopped taking them. I put up with this for a few days and then thought enough was enough. Fies the itching frim plaquenil stop Plaquenil hydroxychloroquine 200mg is it causing itchy skin rash., Does anyone who has RA suffer with itchy skin taking. - NRAS Chloroquine phosphate and invertebrates Ok, I just started taking Plaquenil 7 days ago and I just realized I am really really itchy. I looked down at my arms and I have red and white blotchy areas on my forarms. I am starting to itch in my scalp, back, stomach, face and arms now. I think this rash is just starting, so I don't know if it will develope into hives or what. Anyone Get An Itchy Rash From Plaquenil. -. Taking Plaquenil for Rheumatoid Arthritis. Common Plaquenil side effects a study from FDA data - eHealthMe. Apr 10, 2019 Taking Plaquenil long-term or at high doses may cause irreversible damage to the retina of your eye. Stop taking Plaquenil and call your doctor at once if you have trouble focusing, if you see light streaks or flashes in your vision, or if you notice any swelling or color changes in your eyes. Here are 10 things to keep in mind when using Plaquenil Take it on a regular schedule, meaning at the same time each day. Take Plaquenil EXACTLY as prescribed by your physician. Do not stop taking the medication without first speaking to your doctor. Taking Hydroxychloroquine with food and/or milk can help prevent stomach upset. I have had to stop my plaquenil and aside from the fatigue and joint pain that I knew I would have, I also now have a sunburned look on my face when I go out in the sun and itching skin, almost like a hive type rash on my back.