Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take hydroxychloroquine with all of your drugs and health problems. Chloroquine transfection Plaquenil swollen face SIDE EFFECTS. The following adverse reactions have been identified during post-approval use of PLAQUENIL or other 4-aminoqunoline compounds. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. That's a real common side effect of Lupus is unexplained rashes. If you've ever had an allergic reaction to a drug then this is the type of reaction you'd have if you were allergic to the Plaquenil; and they'd stay until the Plaquenil was out of your system. If they're coming and going more than likely it isn't the Plaquenil. Hydroxychloroquine typically is very well tolerated. Serious side effects are rare. The most common side effects are nausea and diarrhea, which often improve with time. Less common side effects include rash, changes in skin pigment such as darkening or dark spots, hair changes, and muscle weakness. For all uses of hydroxychloroquine: WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Do not start, stop, or change the dose of any drug without checking with your doctor. Plaquenil hypersensitivity rash Plaquenil allergy signs - Answers on HealthTap, Plaqunil rash - How to take aralenChloroquine treatment of amoebic liver abscessSle hydroxychloroquine dose Rashes may occur in up to 10% of patients, most commonly morbilliform or psoriasiform. Note that adverse cutaneous reactions to hydroxychloroquine are reported to affect more than 30% of patients with dermatomyositis, compared to a lower risk of rash in patients with cutaneous lupus erythematosus. Hydroxychloroquine DermNet NZ. Hydroxychloroquine Plaquenil. Hydroxychloroquine hypersensitivity rash, hydroxychloroquine.. Hi There, Ok, I just started taking Plaquenil 7 days ago and I just realized I am really really itchy. I looked down at my arms and I have red and white blotchy areas on my forarms. I am starting to itch in my scalp, back, stomach, face and arms now. I think this rash is just starting, so I don't know if it will Re Plaquenil and Sun Exposure Reply #13 on June 12, 2011, AM After a long dark winter of seeing no sun, I finally went into the sun for an hour, early in the morning, and over the next day, developed a red raised rash on all exposed parts, a rash that lasted for several weeks. Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more.