Other times though, the cause of the shedding locks could be the medications used to treat arthritis. Fortunately, hair loss from arthritis medications is not a widespread complication. Chloroquine injection intravenous Plaquenil not working anymore for lupus Plaquenil and taste buds Interesting! I had been losing weight fairly rapidly and without trying before starting on Plaquenil - and it stopped after a few weeks of taking it, as did the alarming hair loss. I had no idea Plaquenil could be a weight gain culprit. I've been on Plaq for 4 years now, and weight gain is a problem. You are supposed to have a blood test every month to check on your liver and kidneys as long term use can affect them. I was told also to keep an eye out for 'floaters' in my eyes, as Plaquenil can cause macular damage to your retinas. I'm only on a low dose, but now have a black line floating over my eye. Folic acid is commonly prescribed with methotrexate to alleviate some of its side effects. Taking this synthetic form of folate, a B-complex vitamin, can help keep your hair healthy, but it has not been found to promote hair growth. Leflunomide Arava Another widely used DMARD for RA with the potential for hair loss is leflunomide. Methotrexate: The most commonly prescribed disease-modifying antirheumatic drug (DMARD) for rheumatoid arthritis, methotrexate is responsible for hair loss in about 1 to 3 percent of people. Still, if your hair is an important part of your identity, it’s not a small matter to you. Can you take plaquenil help hair growth Hydroxychloroquine Plaquenil, Plaquenil Hydroxychloroquine anyone? - Alopecia World Contraindications for plaquenil Plaquenil is a slow-acting drug, meaning that it can take up to 6 months to experience the full benefits of this medication, but it is possible for symptoms to improve in as few as 1 or 2 months. Plaquenil and other antimalarials are the key to controlling lupus long-term, and some lupus patients may be on Plaquenil for the rest of their lives. Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus. Arthritis Medications and Hair Loss Arthritis Foundation. Growing Back that Gorgeous Head of Hair - Lupus, Humor, and.. I read that hair loss can be a side effect but the literature on RX from CVS says that's a "more serious" side effect and I should contact my doctor. However, it seems like there are a lot of posts on here and elsewhere about people losing hair because of Plaquenil. Both can stop hair growth. But if you take methotrexate to suppress your immune system and stop inflammation, you may reverse scarring and hair follicle damage. This can stimulate new hair growth. Although it is very nonspecific and not appropriate for screening in the doctor’s office, you can use the Amsler Grid at home to help detect early problems. Ideal body weight Plaquenil dosing calculations are reprinted with permission from The Lupus Encyclopedia A Comprehensive Guide for Patients and Families, by Donald E. Thomas, published.