Please review the following URL and make sure that it is spelled correctly. Applies to hydroxychloroquine: oral tablet Along with its needed effects, hydroxychloroquine (the active ingredient contained in Plaquenil) may cause some unwanted effects. Taking plaquenil over 2 years Chloroquine and depression Eye damage due to Plaquenil is not common,” he says. “Rarely will anybody who has good vision and minimal symptoms develop loss of central vision or ability to read if annual screening is done and visual are symptoms reported as soon as they occur so the medication can be stopped if toxicity occurs. Your eye care provider can examine the macula and detect subtle changes before you begin to notice any symptoms of problems. As a result, all patients taking plaquenil should have an examination approximately every six months. The macula should be examined through a dilated pupil. The incidence of Plaquenil related macular problems increases. A severe eye problem has happened with Plaquenil hydroxychloroquine. This may lead to lasting eyesight problems. The risk may be higher if you have some types of eye or kidney problems. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Although not all of these side effects may occur, if they do occur they may need medical attention. Plaquenil and vision problems Focus on Eyes Long-term Plaquenil intake can affect your., Conditions Plaquenil-related Eye Problems Eugene Eye Care Is hydroxychloroquine sulfate a blood thinnerHydroxychloroquine sulfate tab 200mg good rxCheap aralen 250Chloroquine cathepsin In rare cases, hydroxychloroquine can cause visual changes or loss of vision. Such vision problems are more likely to occur in individuals taking high doses for many years, individuals 60 years or older, or those with significant kidney disease. At the recommended dose, development of visual problems due to the medication is rare. Hydroxychloroquine Plaquenil. Plaquenil Indications, Side Effects, Warnings -. Common and Rare Side Effects for Plaquenil Oral. Retinal toxicity of Plaquenil may manifest itself with subtle disturbances of the retinal pigment epithelium which may eventually lead to complete destruction of the macula in the form of bull’s-eye maculopathy. When should you see an ophthalmologist when taking Plaquenil? If you take Plaquenil, here is when to see an ophthalmologist Before Plaquenil treatment begins. You will have a “baseline” eye exam. This measures the health of your eyes and looks for retinal or macular disease. Once a year while taking Plaquenil. Apr 20, 2011 Problems with Plaquenil Use Toxic maculopathy associated with chloroquine use was first documented in the literature five decades ago.1 In the United States, Plaquenil––an analog to chloroquine––is used to treat a variety of conditions, including rheumatoid arthritis, lupus and several distinct inflammatory disorders.