Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. I have lupus am allergic to plaquenil substitute Plaquenil dermatomyositis Hydroxychloroquine blurred vision due to Wierd. Plaquenil is an antimalarial and the 400 mg dosage is based on an average 140lb person. It just happens to work to slow the progression of this disease and helps with fatigue.for me my eyes and dry mouth got a little better.joint pain. It is said to be one of the mildest drugs to take to do. Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Sjögren's is an autoimmune disease in which the immune system attacks the moisture creating glands. In mild cases it causes dry eyes and mouth. In more serious cases it can cause organ damage and failure. Sjögren's can also be diagnosed as primary or secondary. What's the deal with the name? Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil causing dry mouth Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria, Plaquenil Oral Uses, Side Effects, Interactions, Pictures, Warnings. Scarring alopecia plaquenil or hydroxychloroquinePlaquenil similar Just went to webmd. and typed in metallic taste in mouth and its called burning mouth syndrome. you can go there and check it out. its in the oral health center. says could be from oral thrush,diabetes, dry mouth, acid reflux, in women during and after menopause. very interesting. hope this helps. hugs. Metallic taste in mouth DailyStrength. What does plaquenil DO? My doctor wants to put me on it but I.. Plaquenil Side Effects on Your Eyes and Vision. Many people with lupus will experience symptoms such as dry eyes and/or a dry mouth. These symptoms are most commonly caused by Sjögren’s pronounced show-gren’s syndrome, an autoimmune disease that causes inflammation and damage to the glands that produce moisture. About one-third of people with SLE have secondary Sjögren’s syndrome. Dry mouth is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 1 month, also take medication Enbrel, and have Osteoporosis. Side effects include irritability, headache, weakness, hair lightening or loss, stomach upset, nausea, dizziness, muscle pain, rash and itching. Rarely, hydroxychloroquine can affect the bone marrow leading to reduced white blood cells leukopenia or platelets thrombocytopenia.