Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Hydroxychloroquine sulfate Hydroxychloroquine long term side effects Plaquenil information sheet Can plaquenil make psoriatic arthritis worse Plaquenil is prescribed to treat inflammation in people with rheumatoid arthritis, lupus and other inflammatory conditions. Plaquenil is also known by its drug name, Hydroxychloroquine. Plaquenil can help reduce joint pain and inflammation, protect against joint damage, and decrease the risk of disability related to arthritis. Affecting nearly 27 million adults in the United States, osteoarthritis OA is a chronic degenerative joint disease characterized by pain in the knees, hands, spine, or hips. 1,2 Rheumatoid. Please I need to find out if anyone who has taken plaquenil has experienced back and hip pain. I started in Oct of 2011 taking 200 mg of plaquenil once a day. In April of 2012 I started taking 400 mg 2 x's a day. I did start to notice that I was having pain when I tried to sleep at night. Mostly in my arms hands and ankles. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. Does plaquenil reduce pain in osteoarthritis Taking Plaquenil for Rheumatoid Arthritis, Does Methotrexate Improve Osteoarthritis Pain? Plaquenil therapy lupus It can reduce skin problems in lupus and prevent swelling/pain in arthritis, though it is not known exactly how the drug works. OTHER This section contains uses of this drug that are not listed in the approved professional labeling for the drug, but may be prescribed by your health care professional. HYDROXYCHLOROQUINE - ORAL Plaquenil side effects, medical.. Plaquenil and pain" Rheumatoid Arthritis Community - Support Group. Plaquenil From Malaria Treatment to Managing Lupus, RA - Page 3 of 6.. This "dendritic deactivation" I made that phrase up helps reduce your immune system being silly and inflaming your joints. My sister was dx'd with Inflammatory Arthritis and Plaquenil sent her into remission some years ago now. Though it's my personal opinion that she actually has Psoriatic Arthritis and a Rheumy of limited intellect! Inflammatory osteoarthritis is generally treated with nonsteroidal anti-inflammatory drugs and, very rarely, corticosteroid injections directly into the affected joints. The disease-modifying antirheumatic drugs, such as methotrexate and leflunomide Arava prescribed for RA are not appropriate for this type of arthritis. Disease-modifying antirheumatic drugs DMARDs are not effective treatments for hand or knee osteoarthritis OA, according to a new meta-analysis. The drugs are commonly used to treat rheumatoid arthritis RA and other forms of inflammatory arthritis, but researchers in the United Kingdom UK found they were no better than placebo for OA pain.