How common is chloroquine retinopathy

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  1. PrevacRx User

    How common is chloroquine retinopathy


    Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it.

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    However, the study noted serious side effects to the use of chloroquine as a treatment. The study reads “One often cited side effect is chloroquine retinopathy, which can result in permanent. Keep chloroquine daily dose at 3 mg/kg/day and cumulative dose at 460 gm to reduce chances of retinopathy ; Keep hydroxychloroquine daily dose at 6.5mg/kg/day and cumulative dose at 1000gm to reduce chances of retinopathy ; Recognize that patients with renal failure are at unusually high risk of retinal toxicity Introduction Chloroquine and its derivatives are being widely used today for the treatment of such diseases as disseminated lupus erythematosus, discoid lupus, light sensitivity eruptions, sarcoid, asthma, skin tumors, rheumatoid arthritis, and other collagen diseases. Corneal changes were noted soon after the introduction of these drugs, and have been well documented in the literature. 1-14.

    The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead.

    How common is chloroquine retinopathy

    Common Medications That May Be Toxic to the Retina, Chloroquine and Hydroxychloroquine Side Effects of.

  2. Lysosomotropic agent chloroquine
  3. Objective. The effect of chloroquine toxicity on color vision is unclear. The authors identified the color defects seen in chloroquine retinopathy and determined the sensitivity and specificity of clinical color vision tests for detecting the presence of previously diagnosed chloroquine retinopathy.

    • Detection of color vision defects in chloroquine retinopathy..
    • Chloroquine Retinopathy A Report of Eight Cases with ERG..
    • Retinal Physician - Hydroxychloroquine Maculopathy An Update on..

    Chloroquine is a potent drug used for the treatment of various diseases, including malaria and a range of connective tissue disorders. Chloroquine retinopathy is an important complication that may appear even years after cessation of the drug, presenting with impaired visual acuity, central vision loss and progressive damage that could result in irreversible blindness. Hydroxychloroquine and Chloroquine Retinopathy is the first single-source book on the subject and is essential for the practicing ophthalmologists, rheumatologists, dermatologists, and internists who prescribe these drugs. It covers clinical topics such as signs and symptoms of toxicity, toxicity screening, ancillary testing, to whom and why. Some patients, toxicity may first present as pericentral retinopathy and thus requires screening outside the macula. We assume chloroquine retinopathy follows a similar course as hydroxychloroquine retinopathy and so these guidelines also apply to patients taking chloroquine therapy.

     
  4. profitext New Member

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  6. sergeykur XenForo Moderator

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