It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Plaquenil injections Production of chloroquine High blood pressure has happened with leflunomide. Have your blood pressure checked as you have been told by your doctor. Talk with your doctor before getting any vaccines while you take leflunomide and after you stop taking it. Vaccine use with leflunomide may either raise the chance of an infection or make the vaccine not work as well. Leflunomide is the generic form of the brand-name medicine Arava, which is used to treat rheumatoid arthritis a condition in which the body attacks its own joints. This prescription medication. Plaquenil Interactions. Be extra careful about taking medicines that affect your blood cells or immune system, or that may be harmful to your liver when you are taking Plaquenil. Leflunomide. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Interactions with plaquenil and leflunomide Arava and Hydroxychloroquine sulfate drug interactions., Leflunomide Arava - Side Effects, Dosage, Interactions. Side effects of plaquenil 200 mgPara que sirve el hydroxychloroquine 200 mg Hydroxychloroquine sulfate Plaquenil ® can potentially interact with a few other medications. Some of these medicines that may lead to hydroxychloroquine drug interactions include Certain beta blockers, such as Bisoprolol Zebeta ® Metoprolol Lopressor ®, Toprol XL ® Propranolol Inderal ® Sotalol Betapace ® Timolol Blocadren ® Drug Interactions With Hydroxychloroquine. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. Arava and Plaquenil drug interactions - eHealthMe. Apr 13, 2005 The Combination of Leflunomide Arava and Methotrexate is Safe & Efficacious for the Treatment of Rheumatoid Arthritis. Methotrexate MTX, an anti-metabolite that inhibits purine pathways, has been the hallmark of standard of care for many years in the treatment of rheumatoid arthritis RA. The doctor then kept me on my plaquenil and added Leflunomide Arava to replace the methotrexate. My mouth sores went away and I quit having the days of sickness from the methotrexate. There may be something better out there, but for me the Arava has made a big difference. We would like to show you a description here but the site won’t allow us.