It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Can plaquenil lower antibodies to thyroid Chloroquine sensitive Imuran plaquenil together headache Hydroxychloroquine structure Patients in this new study 2 mostly had been prescribed routine doses of HCQ by prior standards, but the average use was approximately 5.0 mg/kg of real weight because of varying compliance and body habitus. Children—Dose is based on body weight and must be determined by your doctor. The dose is usually 5 milligram mg per kilogram kg of body weight once per week on the same day each week starting 2 weeks before traveling to an area where malaria occurs, and continued for 8 weeks after leaving the area. For treatment of malaria Feb 19, 2020 Rheumatoid Arthritis. The action of hydroxychloroquine is cumulative and may require weeks to months to achieve the maximum therapeutic effect see CLINICAL PHARMACOLOGY. Initial adult dosage 400 mg to 600 mg 310 to 465 mg base daily, administered as a single daily dose or in two divided doses. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis (or juvenile idiopathic arthritis) and other autoimmune diseases. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Normal plaquenil dose Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria, Chloroquine Oral Route Proper Use - Mayo Clinic Hydroxychloroquine pregnancy classWill hydroxychloroquine cause high blood pressureChloroquine mechanismPlaquenil and prednisone will i lose weight or gain weightWhat does hydroxychloroquine treat Nov 25, 2019 Initial dose 400 mg 310 mg base orally 1 to 2 times a day; this dose may be continued for several weeks or months, depending on patient response. Maintenance dose 200 to 400 mg 155 to 310 mg base orally daily. Comments -Each dose should be taken with a meal or a glass of milk. Hydroxychloroquine Dosage Guide with Precautions -. Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects.. Hydroxychloroquine dosage recommendations often ignored.. Regarding hydroxychloroquine levels and lupus activity, Costedoat- Chalumeau et al 24 measured whole blood levels in 143 individuals taking a standard dose of 400 mg per day and found a lower hydroxychloroquine level in those with active disease and that lower baseline levels were predictive of disease flare. AAO revised guidelines. The AAO published dosing and screening recommendations for chloroquine and hydroxychloroquine in 2016, revising previous recommendations published in 2011. The current maximum daily HCQ dose recommended by the AAO is 5 mg/kg of real weight. The 2011 guidelines suggested a maximum dose of 6.5 mg/kg of ideal weight. A cumulative dose of 1000g of hydroxychloroquine or 460g of chloroquine was likely the largest risk factor, which was typically achieved after 5-7 years of a typical dosage 8, 10. However, there have been case reports of patients with hydroxychloroquine toxicity as early as 1.9 months after starting treatment 11.