I have been on plaquenil for over a year and a half and methotrexate since September. I get my eyes checked every six months and I am now at once a month on blood work for my liver enzymes (used to be every 2 weeks). I have lupus which mainly affects my joints and skin. One affects your eyes more and one affects your liver more. I would appreciate any comments or advice from everyone. Wannabe Hi, I am on both methotrexate and plaquenil. Wannabe To Be Free To Roam Sorry to hear that you are having a lot of pain with your RA. Pct and hydroxychloroquine mechanism Chloroquine cost boots Malaria dominican republic chloroquine resistance Rising cost of plaquenil How to use Plaquenil. Lupus and/or rheumatoid arthritis patients will most likely take this medication by mouth, usually once or twice daily or as directed. Hydroxychloroquine generally is given to adults in doses of 200 mg or 400 mg per day. In some cases, higher doses can be used. Hydroxychloroquine is commonly used alongside other disease-modifying drugs including methotrexate – especially for rheumatoid arthritis. However, some drugs can interact with hydroxychloroquine. Indigestion remedies for example, antacids including some over-the-counter preparations can stop hydroxychloroquine being absorbed. Mar 17, 2019 An overdose of hydroxychloroquine can be fatal, especially in children. Take hydroxychloroquine for the full prescribed length of time for malaria. Your symptoms may improve before the infection is completely cleared. When treating lupus or arthritis, tell your doctor if your symptoms do not improve after 6 months of treatment. I wish you well with this decision and the results. Your chances of problems with the methotrexate are a bit larger. deductible (I am at about $2,500 - $3,000 right now). My rheumy recently added Imuran (instead of methotrexate). So, what do yall know about the side effects of both and the benefits of both? Do i need hydroxychloroquine with methotrexate Which would you pick and why? - Plaquenil or Methotrexate, Hydroxychloroquine Side-effects, uses, time to work Plaquenile alcohol Does anyone know if hydroxychloroquine and methotrexate can cause weight loss. your MTX dose is very small so maybe you need to talk to your rheumatologist about. Does anyone know if hydroxychloroquine and. - HealthUnlocked. Hydroxychloroquine Uses, Dosage & Side Effects -. Methotrexate vs Plaquenil Comparison -. Try to avoid people with infections like colds or flu. Wash your hands regularly. Tell your doctor if you have fever, chills, or a cough. Don’t take live vaccines like the nasal flu mist, measles, mumps, or shingles shots while you take methotrexate. Jun 09, 2006 Lipsky PE, van der Heijde DM, St Clair EW et al 2000 Infliximab and methotrexate in the treatment of rheumatoid arthritis. Anti-Tumor Necrosis Factor Trial in Rheumatoid Arthritis with Concomitant Therapy Study Group. NEJM 394–1602 Summary. Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more.