I started Plaquenil last week and so far the side effects are dizziness, nausea and tummy feeling weird. I was just wondering has long it takes to adjust and if taking twice the dose will result in higher discomfort. Discoid lupus plaquenil Plaquenil ask doctor Hydroxychloroquine sulfate tablets usp 200 mg side effects Im chloroquine dosage for adults Then, 6.5 mg per kg of body weight taken 6 hours, 24 hours, and 48 hours after the first dose. However, dose is usually not more than 800 mg for the first dose and not more than 400 mg for the next doses. Children—Dose is based on body weight and must be determined by your doctor. Had headaches with the plaquenil so went to the sulfar and predisone. Sulfar was a waste of time and since I had a little help from the plaquenil he switched me back to that with pain meds for the headaches and body. Recently i went back for app. and plaquenil had stopped doing anything so he added the methotrexate to it. I did not want to take it. Shadeseeker 07/01/2009. I take Plaquenil for Lupus and it takes 4 to 6 months. For me, it always seems to take 6 months for me to feel the full effect and a marked improvement in my fatigue & joint pain. Also, any tips on how to keep up with taking them on schedule? I have to take Plaquenil, Naturethroid and Vitamin D, everyday . I'm having lots of trouble falling asleep (been having it for a while), not sure if it's getting worse due to the pills. How longbto take plaquenil after alcohol Plaquenil Oral Uses, Side Effects, Interactions., What next if plaquenil doesn't work? - Can glucose and bind to chloroquineGlioblastoma chloroquine The adult dose of Plaquenil to treat an acute attack of malaria is an initial dose of 800 mg followed by 400 mg in six to eight hours and 400 mg for two more days. To treat lupus erythematosus, the average adult dose is 400 mg once or twice daily. Plaquenil may interact with acetaminophen, cancer medications. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. When does the plaquenil kick in? DailyStrength. Plaquenil Uses, Dosage & Side Effects -. I'm terrible at remembering. I have to take Plaquenil, Naturethroid and Vitamin D, everyday. My other concern, I'm a wine drinker, a couple of glasses a week, mostly weekends or after a long day at work. I was researching on wine alcohol use while on Plaquenil and I'm a bit confused. I'm also taking Naturethoid. It sounds like you're doing a good job of it yourself, but I would say go very slowly off of it. Plaquenil takes a long time to build up in your body and therefore also will take awhile to really leave your body as well. So you're not going to get a good picture in one months time what the reduction of the plaquenil has had on you. Plaquenil is the brand name of hydroxychloroquine, a drug used to prevent or treat malaria 2. Plaquenil is also used for long-term treatment of autoimmune diseases such as rheumatoid arthritis RA and systemic lupus erythmatosis. According to the Mayo Clinic, it can take up to six months' constant use before an effect is seen in RA 1.