Please review the following URL and make sure that it is spelled correctly. Anita- It is hard to say whether I noticed a difference when I first went on plaquenil, because I was also on 10mg of prednisone at that time, and I didn't start weaning down from that until I had been on plaquenil for a few months. Hydroxychloroquine scleroderma Hydroxychloroquine high dose Plaquenil preretinopathy In the short term, it can cause accommodation disturbance, blurred vision, halos, photophobia reversible on discontinuation. Very rarely, Stevens-Johnson syndrome/toxic epidermal necrolysis can occur. Very rarely, the skin and mucosa can change to a black-blue colour in a process called dyschromia. Hydroxychloroquine can also exacerbate psoriasis. Plaquenil hydroxychloroquine is an antimalarial medication used to treat or prevent malaria, a disease caused by parasites, which enter the body through the bite of a mosquito. Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Plaquenil is available in generic form. Saturday was a week since I stopped taking Plaquenil, aka Hydroxychloroquine, per my doctor's instructions, and I think I am going through some form of withdrawal. I took the drug as a treatment for sarcoidosis and one of the side effects is a reduction in white blood cells, which is what has happened to me. To answer some of your other questions, it was the same timeframe for me. I can say that the prednisone wean was successful, even after having only been on plaquenil a few months. Plaquenil discontinuation syndrome Polymyalgia Rheumatica Plaquenil hydroxychloroquine., Plaquenil vs. Prednisone Prescription Treatment for. Does prednisone and plaquenil work for ankylosing spondylitits Discontinuation of hydroxychloroquine could decrease hydrocodone plasma concentrations, decrease opioid efficacy, and potentially lead to a withdrawal syndrome in those with physical dependence to hydrocodone. Plaquenil hydroxychloroquine sulfate dose, indications.. Plaquenil Withdrawal – Life As An Anomaly. The Risk of Retinal Toxicity with Plaquenil. Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as. Find information about common, infrequent and rare side effects of Plaquenil Oral. Withdrawal syndrome is found among people who take Plaquenil, especially for people who are female, 50-59 old also take medication Lyrica, and have Fibromyalgia. This study is created by eHealthMe based on reports of 48,911 people who have side effects when taking Plaquenil from Food and Drug Administration FDA, and is updated regularly.