It is used to prevent and treat acute attacks of malaria. It is also used to treat discoid or systemic lupus erythematosus and rheumatoid arthritis in patients whose symptoms have not improved with other treatments. Macular degeneration from plaquenil Plaquenil and surgery risk Chloroquine phosphate doctors foster and smith Hydroxychloroquine Plaquenil, chloroquine Aralen, and quinacrine Atabrine are medications that were originally used to prevent or treat malaria. However, during World War II it was also found that these medications were effective in treating the symptoms of lupus. There are several drugs now that you can take instead of the plaquenil. these type of drugs they have now work in a different way then the methotrexate and plaquenil. most of these drugs you will still take the methotrexate. Hydroxychloroquine can lower the seizure threshold; therefore, the activity of antiepileptic drugs may be impaired with concomitant use. Perampanel Moderate Caution is warranted with the coadministration of hydroxychloroquine and antiepileptic drugs, such as perampanel. Hydroxychloroquine comes as a tablet to take by mouth. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information. Another medication that can be taken with plaquenil Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects., Is there a drug that I can take to replace plaquenil? Chloroquine autophagy lysosomeSide effects of chloroquine phosphate tabletsPlaquenil itching side effects Re don't want to take plaquenil anymore I am under the care of an internist, he gave me a prescription for plaquenil, and he told me 3 times already that he wanted me going to a rhematologist and for some reason I don't get the referral or a call with an appt. Immune & Autoimmune - Lupus don't want to take plaquenil anymore. Plaquenil hydroxychloroquine sulfate dose, indications.. Plaquenil - Uses, Side Effects, Interactions -. When phenothiazine medications, certain beta blockers, or certain parasite medicines are taken together with Plaquenil, interactions can occur that may affect the drug levels in your blood. This could increase your risk for side effects or decrease the effectiveness of the medicines. Tell your doctor and pharmacist what prescription and nonprescription drugs you are taking, especially acetaminophen Tylenol, others, digoxin Lanoxin, iron-containing medications including multivitamins, isoniazid Nydrazid, methotrexate Rheumatrex, niacin, rifampin Rifadin, Rimactane, and vitamins and herbal products. The adult dose of Plaquenil to suppress malaria is 400 mg on the same day each week. The pediatric weekly suppressive dosage is 5 mg/kg of body weight. The adult dose of Plaquenil to treat an acute attack of malaria is an initial dose of 800 mg followed by 400 mg in six to eight hours and 400 mg for two more days.