Chloroquine resistance in myanmar

Discussion in 'Hydroxychloroquine Sulfate' started by a_richkovsky, 08-Mar-2020.

  1. nurbek Moderator

    Chloroquine resistance in myanmar


    Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it.

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    All the chloroquine-resistant cases were again treated with chloroquine 1500 mg and no further recrudescence or relapse was detected on days 21 and 28. This study indicates that chloroquine is losing its efficacy against P. vivax in Myanmar. Red Pages Malaria Information and Prophylaxis, by Country. Links with this icon indicate that you are leaving the CDC website. The Centers for Disease Control and Prevention CDC cannot attest to the accuracy of a non-federal website. South East Asia has been implicated in the rise of resistance to both chloroquine and artemisinin. The main explanation is that lower levels of natural malaria immunity exist in the region than in Africa. With no background resistance, the drugs have to do all the work in infected patients in South East Asia.

    The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead.

    Chloroquine resistance in myanmar

    Guidelines for Treatment of Malaria in the United States., CDC - Malaria - Travelers - Malaria Information and Prophylaxis, by Country

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  7. Plasmodium vivax malaria remains a major public health burden in Myanmar. Resistance to chloroquine CQ, the first-line treatment for P. vivax, has been reported in the country and has potential to undermine local control efforts.

    • Chloroquine efficacy for Plasmodium vivax in Myanmar in..
    • Malaria on Myanmar-India border is 'huge threat' - BBC News.
    • Border Malaria Associated with Multidrug Resistance on Thailand-Myanmar..

    Rare cases of chloroquine-resistant P. vivax have also been documented in Burma Myanmar, India, and Central and South America. Persons acquiring P. vivax infections from regions other than Papua New Guinea or Indonesia should initially be treated with chloroquine. Malaria. Chloroquine has long been used in the treatment or prevention of malaria from Plasmodium vivax, P. ovale, and P. malariae, excluding the malaria parasite Plasmodium falciparum, for it started to develop widespread resistance to it. Chloroquine has been extensively used in mass drug administrations. A study defining the P. vivax chloroquine-resistant phenotype in Myanmar by therapeutic efficacy study during 2006–2009 reported a clinical failure after 28 days of treatment in Kawthaung 1.7% and two further treatment failures in Buthidaung 3.3%.

     
  8. ss* New Member

    Chloroquine has long been used in the treatment or prevention of malaria from Plasmodium vivax, P. malariae, excluding the malaria parasite Plasmodium falciparum, for it started to develop widespread resistance to it. Chloroquine Suicide Chloroquine Oral Uses, Side Effects, Interactions, Pictures, Warnings. G adeathofone’sown.” RichardMacDonald,M. D. HumaneSelf-ChosenDeath
     
  9. klikmcl Well-Known Member

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