It works by preventing or treating malaria, a red blood cell infection transmitted by the bite of a mosquito. However, this medicine is not used to treat severe or complicated malaria. Chloroquine ich treatment Will hydroxychloroquine help osteoarthritis Aug 20, 2013 I thought that maybe the Plaquenil caused my weakness as it increased vastly right after I started it, but I think it was the flexeril I was taking for the twitching and jerking as I stopped that and the weakness became better. My PCP told me that it's rare to have weakness with plaquenil but more common with flexeril. Plaquenil antibiotics are part of the fluoroquinolone antibiotics. Muscle weakness is a side effect. I would be very cautious! Quinolone antibiotics are chemotherapeutic and late side effects months to years later are common. Mar 14, 2011 I don't have an answer for you, but I've been on Plaquenil for 2 years and have recently been dealing with the muscle weakness issue which infers muscle loss? Rheumy checked CPK and the result was actually abnormally low - so I'm not sure what that means - since it's a high result that is the red flag for muscle damage. It is also used to treat acute and chronic rheumatoid arthritis. Hydroxychloroquine is used to treat discoid lupus erythematosus (DLE) or systemic lupus erythematosus (SLE or lupus). Plaquenil muscle weakness How Lupus Affects the Muscles, Tendons and Joints Lupus., Plaquenil weakness - Road Back Foundation Plaquenil generic and brand namesWhy would a hiv patient use plaquenilPlaquenil burning eyesHow does chloroquine prevent malariaPlaquenil cost cvs Can Plaquenil cause Muscle Weakness? Muscle Weakness is a known side effect of Plaquenil. Complete analysis from patient reviews and trusted online health resources, including first-hand experiences. Can Plaquenil cause Muscle Weakness? - Treato. Muscle Weakness? -. Ask the Expert Plaquenil and Sjögren’s. Feb 19, 2020 Common side effects may include headache, dizziness, ringing in your ears; nausea, vomiting, stomach pain; loss of appetite, weight loss; mood changes, feeling nervous or irritable; skin rash or itching; or. hair loss. May 04, 2015 Just got back from my neurologist and I am officially a "zebra" - my extreme and fast developing proximal muscle weakness myopathy is from doesn't mean I don't have any muscle weakness from the scleroderma, but the crazy, out-of-control weakness was from Plaquenil. Muscle weakness; Bleeding or bruising of the skin; Irregular heartbeat; Mood or mental changes, such as confusion or other changes in thinking, feelings, or behavior; Bleaching or loss of hair.