Plaquenil retinal screening interval

Discussion in 'North West Pharmacy Canada' started by sergey66, 29-Feb-2020.

  1. iamliss Moderator

    Plaquenil retinal screening interval


    She suffered from Sjogren syndrome and inflammatory arthritis and was currently treated with prednisone and methotrexate. She was previously treated with hydroxychloroquine (Plaquenil) 200mg bid (6.5mg/kg) for 10 years, which was stopped one year prior to presentation.

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    Plaquenil prolongs the QT interval. Ventricular arrhythmias and torsades de pointes have been reported in patients taking Plaquenil see OVERDOSAGE. Therefore, Plaquenil should not be administered with other drugs that have the potential to prolong the QT interval see DRUG INTERACTIONS. Nov 01, 2015 The incidence of retinal toxicity is associated with the cumulative dose of the drug, increasing significantly beyond 1,000 g of HCQ. This cumulative dose is created when the common dose of 400 mg/day is used for 6.8 years. Hydroxychloroquine is metabolized and secreted by both the liver and the kidneys. As patients are started on hydroxychloroquine, they will have a baseline retinal screen usually at 3 months but certainly within 12 months of starting, organised by the specialist.

    Review of systems: Blurred vision, halos, dry eye, dry mouth, gastroesophageal reflux, joint pain Pupils: Reactive to light in each eye from 5 mm in the dark to 2 mm in the light. Extraocular movements: Full, both eyes (OU) Confrontation visual fields: Full OU Intra-ocular pressure The optic nerves appeared healthy with a 0.3 cup-to-disc ratio. Past Ocular History: None Medical History: Sjogren syndrome and inflammatory arthritis, supraventricular tachycardia, anxiety, depression, peptic ulcer disease Medications: prednisone, methotrexate, amitriptyline, ranitidine, estradiol, tizanidine, diltiazem, Restasis Allergies: codeine, droperidol Family History: heart disease, arthritis, cancer Social History: occasional alcohol but no tobacco or intravenous drug use.

    Plaquenil retinal screening interval

    Hydroxychloroquine and Chloroquine Retinopathy., Retinal Physician - Hydroxychloroquine Maculopathy An Update.

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  7. The treatment for early toxicity usually requires stopping Plaquenil. Patients taking Plaquenil should have an early baseline assessment of visual acuity, macular appearance and central field sensitivity. The macular appearance and function should be checked at intervals of 6 to 12 months.

    • Plaquenil Toxicity Screening - Retina Group of New York.
    • Hydroxychloroquine and Retinal Screening.
    • AMERICAN COLLEGE OF RHEUMATOLOGY.

    Hydroxychloroquine HCQ, sold under the brand name Plaquenil among others, is a medication used for the prevention and treatment of certain types of malaria. Specifically it is used for chloroquine-sensitive malaria. Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda. It is taken by mouth. Your ophthalmologist can use this image to look for early retinal damage. Multifocal ERG This test looks at cells in the retina called rods and cones. The test measures how well these cells respond to light. It can find retinal damage from Plaquenil. Photos A special camera takes pictures of the retina. Photos show damaged areas as small. If, and only if, the patient is at the recommended maximum daily dose and does not fall into a higher risk category, the screening interval is 5 years after the initial evaluation.

     
  8. Solmyr Moderator

    Hydroxychloroquine is used to prevent or treat malaria infections caused by mosquito bites. Taking Plaquenil for Rheumatoid Arthritis Hold the immunomodulators for surgery? Maybe yes, maybe no. Perioperative Management of Medications Used in the Treatment.
     
  9. Sash_zp Guest

    Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses Feb 19, 2020 Plaquenil hydroxychloroquine is an antimalarial medication used to treat or prevent malaria, a disease caused by parasites, which enter the body through the bite of a mosquito. Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus.

    Hydroxychloroquine Side-effects, uses, time to work