She said the muscles were a touch irritated as well. Diagnosed small fiber p neuropathy due to autoimmune issues and recommended I get a second opinion from a different rheumatologist and for treatment of the neuropathy. Drugs.com hydroxychloroquine Hydroxychloroquine effect on eyes Plaquenil screening guidelines aao Does hydroxychloroquine cause leukopenia In fact, as time passes, it becomes severe — turning from small fiber neuropathy to large fiber neuropathy. Michael Polydefkis, a professor of neurology, also working at Johns Hopkins reached a conclusion through another study that neurological dysfunction symptoms such as difficulty in walking, blood pressure regulation and problems with balance are the top symptoms that push small fiber neuropathy further. Individuals with small fiber neuropathy cannot feel pain that is concentrated in a very small area, such as the prick of a pin. However, they have an increased sensitivity to pain in general hyperalgesia and experience pain from stimulation that typically does not cause pain hypoesthesia. Diagnosed small fiber p neuropathy due to autoimmune issues and recommended I get a second opinion from a different rheumatologist and for treatment of the neuropathy. Usually she said small fiber neuropathy is reversible, with good aggressive treatment. I know this is true as it reversed itself last time, though it was not this bad. Thanks for the information, Tammy15 mg prednisone150 mg Imuran.5 mg clonazepam Hi Tammy, This is what Wikipedia says about treatment of Small Fiber Neuropathy: Treatment is based on the underlying cause, if any. Usually she said small fiber neuropathy is reversible, with good aggressive treatment. Can plaquenil help with small fiber neuropathy Small Fiber Neuropathy Overview – Therapath Neuropathology, Small fiber neuropathy - Genetics Home Reference - NIH Ra hydroxychloroquineChloroquine stock Small Fiber Neuropathy SFN, a type of peripheral neuropathy PN, is a fairly common chronic condition that can develop at any age, with the disease most prevalent in the elderly. While its prevalence is unknown, 1 an estimated 15 million to 20 million people in the U. S. over age 40 have some type of PN. 2 To date, there is no cure for SFN. IVIG for Small Fiber Neuropathy. Small fiber neuropathy and treatment?. Treatment for Autoimmune Small-fiber Neuropathy 2018-02-16.. Background Small fiber neuropathy typically presents as a sensory syndrome characterized by burning pain, most often in a length-dependent pattern. A variety of immunological syndromes present with a similar neuropathy, including a paraneoplastic syndrome associated with anti-Hu antibodies, but other antibody targets are not well understood. Special diagnostic tests, including the technique of superficial, punch skin biopsies small biopsies of 3 millimeters and not requiring any stitches, can help in the diagnosis. A relatively rare neuropathy can cause significant weakness in Sjogren's patients. Small fiber neuropathy is a type of peripheral neuropathy. Peripheral neuropathies affect the peripheral nervous system. This includes the nerves outside of the brain and spinal cord. With small fiber neuropathy, the narrow nerve fibers of the peripheral nervous system are affected.