Yesterday my rheumatologist started me on hydroxychloroquine as well. Is anyone else on this combination and have you had any problems with it as I know hydroxychloroquine can cause eye sight problems. Hydroxychloroquine routine diagnostics Do you have to wean off plaquenil Does anyone take methotrexate and hydroxychloroquine and has anyone had problems with hydroxychloroquine. Yep I have been on these two for 3 years, plus Humira for 2 yrs, had eyes checked plaquinil damage to eyes is rare. I take 200 mg plaquinil daily,& 20 mg MTX & bloods / liver coping fine, everyone is different but I seem to tolerate well. Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as. Humira adalimumab is good for treating many autoimmune conditions, but it can also cause serious side effects. Plaquenil hydroxychloroquine is an effective medication for autoimmune conditions and malaria that comes with less side effects than other DMARDs. Recently my eyes have felt sore and, after posting a question on this site, I am seeing my GP on Monday. Thanks Hi Catjones I have been taking this combination, started on both of them in January this year. Humira methotrexate plaquenil Methotrexate and Humira DailyStrength, Plaquenil Hydroxychloroquine - Side Effects, Dosage. Side effects of plaquenil 400 mgPlaquenil cardiotoxicityChecking vision plaquenilWhy would plaquenil not work on raRisk of plaquenil retinopathy Jan 22, 2016 Glenn Frey's death, tied in part to rheumatoid arthritis medications he was taking, is a 'wake-up call' about the dangers of powerful drugs used to treat the condition, a top doc says. It should push arthritis patients and their doctors to seek out safer available alternatives. Safe, Natural Alternatives to Arthritis Drugs Top Doc.. Compare Adalimumab vs Plaquenil -. Patient Assistance & Copay Savings Card for HUMIRA® Cost. Methotrexate vs plaquenil side effects long term and short term The only problem is the Plaquenil causes severe headaches that interfer with my daily activities also. But the Dr suggested I try Methotrexate instead. Methotrexate MTX, trade names Trexall™ and Rheumatrex™ is the most commonly used DMARD in the treatment of RA, in up to 80% of patients in some studies. MTX is a folic acid analog, which when administered in high doses blocks purine and pyrimidine synthesis. I am on both methotrexate and plaquenil. I have been on plaquenil for over a year and a half and methotrexate since September. I have had no side effects from either one. I get my eyes checked every six months and I am now at once a month on blood work for my liver enzymes used to be every 2 weeks.