Hydroxychloroquine is available as the brand-name drug Plaquenil. Generic drugs usually cost less than the brand-name version. Hydroxychloroquine may be used as part of a combination therapy. Tumors associated with plaquenil In regards to malaria what is chloroquine resistance Aug 29, 2014 Several risk factors may increase the likelihood of retinal toxicity from Plaquenil such as, age of greater than 60 years, daily dose more than 6.5 mg/kg; use of the drug more than 5 years, obesity, preexisting retinal disease and, renal or liver failure. For the Consumer. Continuing ringing or buzzing or other unexplained noise in the ears. feeling of constant movement of self or surroundings. irritability. nausea. nervousness. nightmares. sensation of spinning. shakiness and unsteady walk. uncontrolled eye movements. unsteadiness, trembling, or. What Are Side Effects of Plaquenil? nausea, vomiting, stomach pain or cramps, loss of appetite, weight loss, diarrhea, dizziness, spinning sensation, headache, ringing in your ears, Hydroxychloroquine is used to treat lupus erythematosus and rheumatoid arthritis. It isn’t fully understood how this drug works to treat lupus erythematosus or rheumatoid arthritis. That means you may need to take it with other drugs. It treats malaria by killing the parasites that cause the disease. Dangers of plaquenil Plaquenil Oral Uses, Side Effects, Interactions., Plaquenil Side Effects Common, Severe, Long Term - Can plaquenil cause inflammation in my respiratory systemPlaquenil rash wont go awaySudden blurry vision with plaquenil have floatersCan plaquenil affect thyroid All of these risks are very low and the benefits of Plaquenil hydroxychloroquine will far out weight the risks. Doctors give trusted answers on uses, effects, side-effects, and cautions Dr. Ali on dangers of plaquenil Potential Plaquenil hydroxychloroquine side effects include GI intolerance, itching, rash, muscle weakness and eye inflammation retinopathy. Dangers of plaquenil - Answers on HealthTap. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis.. Plaquenil is the brand name of hydroxychloroquine, a drug used to prevent or treat malaria. Plaquenil is also used for long-term treatment of autoimmune diseases such as rheumatoid arthritis RA and systemic lupus erythmatosis. Plaquenil hydroxychloroquine is in a class of drugs called disease-modifying anti-rheumatic drugs, which are used to decrease inflammation, pain and joint damage. While today it is used to treat autoimmune conditions, such as rheumatoid arthritis and lupus, it was originally used as an anti-malaria drug. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria.