Chloroquine phosphate, 250 mg twice daily, or hydroxychloroquine sulfate, 200 mg twice daily, was administered for a period of 6 to 21 months. Patients had regular clinical evaluation, determination of serum and cerebrospinal fluid angiotensin-converting enzyme level, computed tomography or magnetic resonance imaging, chest radiography, lung function testing, and slit-lamp examination of the eyes. Hydroxychloroquine causing rash where Could you develop a rash 3 weeks after starting hydroxychloroquine Hydroxychloroquine rob holland Chloroquine intercalating dna Healthgirl. Another thing I should say. The Plaquenil is used to treat the Sjogren's, not directly treat the neuropathy. If she feels the neuropathy is caused by the Sjogren's, then I guess she feels treating the underlining cause will help the SFN. Side Effects Rash on neck began on day 8. Increased nerve pain I have idiopathic neuropathy. Anxiety seems to increase daily which causes me to eat and have trouble getting to sleep. Plaquenil and small fiber neuropathy I used Plaquenil years ago for extreme muscle and joint issues and it seemed to work fine. All my issues were resolved over a years time on low doses. Magnetic resonance imaging with gadolinium was most helpful in supporting the diagnosis of sarcoidosis and monitoring the course of the disease. Chloroquine or hydroxychloroquine either stabilized symptoms or controlled neurological symptoms in 10 of 12 patients. Cerebrospinal fluid abnormalities, including lymphocytosis, were seen in 3 patients. Does plaquenil help neuropathy Study Raises Questions about Sjogren's and Plaquenil, Hydroxychloroquine Sulfate Neuropathy Peripheral Reports. Taking plaquenil over 2 yearsPlaquenil cardiacChloroquine paludismePlaquenil dose for sjogrens But I have noticed the neuropathy improving lately, & as I write this, wonder if the plaquenil has had anything to do with the improvement. Sorry for the long reply, but I hope this kind of helps to answer your question. I also hope this combo of meds will help with your neuropathy & sooner rather than later! Good-luck & keep in touch! Aimee Mycophenolate mofetil with Plaquenil Mayo Clinic Connect. Plaquenil and small fiber neuropathy - NeuroTalk Support Groups. PLAQUENIL HYDROXYCHLOROQUINE SULFATE TABLETS, USP DESCRIPTION. Thomas is enthusiastic about the updated guidelines, although he worries that the new dosing recommendations have not been widely disseminated to rheumatologists. “I think people with lupus can make a difference by pointing out the new guidelines to their rheumatologists,” he says. “Plaquenil is not deposited into fat,” he explains. Plaquenil is the brand name of hydroxychloroquine, a drug used to prevent or treat malaria 2. Plaquenil is also used for long-term treatment of autoimmune diseases such as rheumatoid arthritis RA and systemic lupus erythmatosis. According to the Mayo Clinic, it can take up to six months' constant use before an effect is seen in RA 1. The latter is related to drug accumulation in melanin-rich tissues. 15,16 Prolonged treatment with chloroquine also can cause toxic myopathy, cardiopathy, and peripheral neuropathy and neuropsychiatric disturbances; all of these reactions improve if the drug is discontinued promptly. 17,18 Both chloroquine and hydroxychloroquine should be used.