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Secretory diarrhea means that there is an increase in the active secretion, or there is an inhibition of absorption. The most common cause of this type of diarrhea is a cholera toxin that stimulates the secretion of anions, especially chloride ions (Cl It continues even when there is no oral food intake. Osmotic diarrhea occurs when too much water is drawn into the bowels. If a person drinks solutions with excessive sugar or excessive salt, these can draw water from the body into the bowel and cause osmotic diarrhea. Osmotic diarrhea can also be the result of maldigestion (e.g. pancreatic disease or coeliac disease), in which the nutrients are left in the lumen to pull in water. Fluoroquinolone antibiotics are commonly used in veterinary medicine to treat susceptible bacterial infections. For large dogs, finding an antibiotic both efficacious and affordable can be challenging. 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