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    Selectivo usado en el tratamiento de enfermedades severas del sistema cardiovascular, especialmente de la hipertensión y el infarto agudo de miocardio (IAM). Es comercializado con el nombre de Lopressor por Novartis, y Toprol-XL (en USA); El compuesto activo del metoprolol es empleado ya sea como metoprolol succinato o metoprolol tartrato (donde 100 mg de metoprolol tartrato corresponden a 95 mg de metoprolol succinato), respectivamente formulado como compuesto de liberación prolongada o de liberación convencional. El metoprolol tiene un punto de fusión muy bajo, alrededor de 45 grados Celsius. Por ello siempre es elaborado en una solución salinizada, como todos los medicamentos con puntos de fusión menores a 100 grados, condición que dificulta su elaboración dentro de un medio de trabajo. La base libre existe como un sólido blanco seroso, mientras el tartrato es un material fino y cristalino. Es metabolizado en el hígado a metabolítos inactivos La dosis inicial es de 100 mg diarios en una o varias dosis, ya se use solo o adicionado a un diurético. La dosis puede ser incrementada a intervalos semanales (o más), hasta que un control óptimo de la presión arterial es alcanzado. flovent for kids Below you will learn more about the fields of application and the mode of action of metoprolol. Please also read the information on the drug groups beta-blockers, antihypertensives, to which the active ingredient metoprolol belongs. Metoprolol is used in the treatment of hypertension, which has no organic causes (essential hypertension), and cardiovascular problems. In addition, metoprolol is prescribed for heart disease associated with inadequate oxygenation of the heart muscle (myocardial insufficiency) and circulatory disorders of the coronary heart disease (coronary heart disease). In this context, metoprolol is used in stable, not causing discomforting angina pectoris. Another area of use of the drug is cardiac arrhythmia associated with too rapid a heartbeat. Metoprolol can have a beneficial effect on these cardiac arrhythmias because it slows down the heartburn.

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