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    Clomid is a popular brand name and nickname for generic clomiphene citrate. It’s an oral fertility medication approved by the U. Food and Drug Administration (FDA) for use in women who are unable to become pregnant. It affects the hormone balance within the body and promotes ovulation. Clomid is only approved by the FDA for use in women, but it’s sometimes prescribed off-label as an infertility treatment in men. Is Clomid an effective treatment for male infertility? Clomid blocks the hormone estrogen from interacting with your pituitary gland. When estrogen interacts with the pituitary gland, less luteinizing hormone (LH) and follicle-stimulating hormone (FSH) are produced. This leads to a decrease in testosterone and therefore decreased production of sperm. Because Clomid blocks estrogen’s interaction with the pituitary gland, there is an increase in LH, FSH, and testosterone in the body. The dose given can range from 12.5 to 400 milligrams (mg) per day. Clomid (clomiphene) is a non-steroidal fertility medicine. It causes the pituitary gland to release hormones needed to stimulate ovulation (the release of an egg from the ovary). Clomid is used to cause ovulation in women with certain medical conditions (such as polycystic ovary syndrome) that prevent naturally occurring ovulation. Clomid may also be used for purposes not listed in this medication guide. You should not use Clomid if you have: liver disease, abnormal vaginal bleeding, an uncontrolled adrenal gland or thyroid disorder, an ovarian cyst (unrelated to polycystic ovary syndrome), or if you are pregnant. You should not use Clomid if you are allergic to clomiphene, or if you have: Do not use Clomid if you are already pregnant. Talk to your doctor if you have concerns about the possible effects of Clomid on a new pregnancy. Clomiphene can pass into breast milk and may harm a nursing baby.

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