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    However, it is not a first line treatment since the development of selective serotonin reuptake inhibitors. Alprazolam is no longer recommended in Australia for the treatment of panic disorder due to concerns regarding tolerance, dependence, and abuse. Most evidence shows that the benefits of alprazolam in treating panic disorder last only 4 to 10 weeks. However, people with panic disorder have been treated on an open basis for up to 8 months without apparent loss of benefit. In the US, alprazolam is FDA-approved for the management of anxiety disorders (a condition corresponding most closely to the APA Diagnostic and Statistical Manual DSM-IV-TR diagnosis of generalized anxiety disorder) or the short-term relief of symptoms of anxiety. In the UK, alprazolam is recommended for the short-term treatment (2–4 weeks) of severe acute anxiety. Benzodiazepines require special precaution if used in children and in alcohol- or drug-dependent individuals. doxycycline long term Anxiety has reached epidemic proportions in the United States with over 40 million people affected. Every year, millions of prescriptions are written for anti-anxiety medications like Xanax and Ativan making them some of the most commonly prescribed drugs. more than $42 billion a year, almost one-third of the country’s total mental health bill. They belong to a group of drugs known as the benzodiazepines. The exact mechanism by which benzodiazepines work is not fully understood, but it’s believed they raise levels of the calming neurotransmitter gamma-aminobutyric acid (GABA) or increase GABA receptor sensitivity. Other medications that belong in this group, commonly referred to as “benzos,” include brand names such as Centrax, Dalmane, Klonopin, Librium, Paxipam, Restoril, Serax, Tranxene, and Valium. These drugs can stop anxiety or a panic attack in its tracks. Relief is experienced quickly — often within 30 to 60 minutes — and generally lasts 11 to 20 hours.

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